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  3. 1. Comparison of Transient Hypocalcaemia Due to Parathyroid Injury in Subtotal versus Total Thyroidectomy
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1. Comparison of Transient Hypocalcaemia Due to Parathyroid Injury in Subtotal versus Total Thyroidectomy

Muzaffar Aziz1, Muhammad Azim Khan2, Ghulam Murtaza1 and Khalid Hussain Qureshi1

ABSTRACT

Objective: The objective of this study was to compare the frequency of transient hypocalcaemia due to parathyroid injury in subtotal versus total thyroidectomy.

Study Design: Quasi Experimental Study.

Place and Duration of Study: This study was conducted in indoor Department of General Surgery Nishtar Hospital Multan from 01-03-2016 to 30-12-2016.

Materials and Methods: 60 patients of either gender and 25-60 year of age admitted for thyroidectomy were included in this study. All patients were divided into two groups. 30 patients were in total thyroidectomy group and 30 patients were in sub-total thyroidectomy group.

Thyroidectomies were performed by a standard procedure of capsular dissection; the total thyroidectomy method included the expulsion of entire gland from one tracheoesophageal section to other. In subtotal thyroidectomy method, complete lobectomy was performed on prevailing lobe and couple of grams of thyroid tissue was left along the posterior aspect of contralateral lobe. Every surgical specimen was subjected for histopathological examination to evaluate the presence of parathyroid gland in surgical specimen. Parathyroid injury and transient hypocalcaemia was noted in both groups.

Results: Age range in this study was from 25 to 60 years with mean age of 44.233±6.77 years in Total thyroidectomy group while 44.466±7.19 years in Sub-total thyroidectomy group. Majority of patients were females in both groups. Postoperative parathyroid injury was seen 36.7% in Total thyroidectomy group as compare to 10% in Sub-total thyroidectomy group (P=0.014). While transient hypocalcaemia was seen 23.3 % in Total thyroidectomy group as compare to 6.7% in Sub-total thyroidectomy group (P=0.070). Majority of transient hypocalcaemia was seen in patients with postoperative parathyroid injury in both groups. 

Conclusion: We conclude that the sub total thyroidectomy has minimum chance of any injury to the parathyroid gland and it is better option for reducing the risk of transient hypocalcaemia. Key Words: Thyroidectomy, Parathyroid injury, Hypocalcaemia

Citation of article: Aziz M, Khan MA, Murtaza G, Qureshi KH. Comparison of Transient Hypocalcaemia Due to Parathyroid Injury in Subtotal versus Total Thyroidectomy. Med Forum 2017;28(2):2-5.