Search Submit Your Manuscript

Become A Member

  1. Home
  2. January 2022
  3. 11.Comparison of Efficacy of Cervical Cerclage and Vaginal Progesterone in the Prevention of Preterm Labour
Article Image
Admin

11.Comparison of Efficacy of Cervical Cerclage and Vaginal Progesterone in the Prevention of Preterm Labour

Sara Fayyaz, Joveria Sadaf, Sana Hafeez, Sana Aara, Aisha Ajmal and
Aslam Mehmood Malik

ABSTRACT

Objective: To compare the efficacy of prophylactic vaginal progesterone with cervical cerclage in women with previous history of preterm birth.

Study Design: Randomized controlled trial study

Place and Duration of Study: This study was conducted at the Department of Obstetrics & Gynecology, Shahida Islam Medical and Dental College (SIMDC), Lodhran from April, 2020 to April, 2021 for a period of one year.

Materials and Methods: 120 women at 14-20 weeks of gestation, who had previous history of preterm birth were included in the study. Women who had rupture of membranes, multiple pregnancy, antepartum hemorrhage and severe intra-uterine growth retardation were excluded. Progesterone pessary 200mg was given vaginally once daily at night till delivery in the Group A and  McDonald’s stitch using prolene 1-0 was applied by the researchers themselves in the Group B. Effectiveness (yes/no) of both methods were noted by the researchers.

Results: The mean age of women in group A was 29.97 ± 5.43 and in group B was 28.63 ± 5.12 years. Majority 68 (56.67%) were between 18 to 30 years of age. Gestational age was from 14 to 20 weeks with mean gestational age of 17.19 ± 1.97 weeks. The mean gestational age in group A was 17.13 ± 1.98 weeks and in group B was 17.23 ± 1.97 weeks. Mean parity was 2.43 ± 0.79. Mean BMI was 29.81 ± 3.11 kg/m2. Efficacy [no preterm birth (<37 weeks)] was 38 (63.33%) in group A (vaginal progesterone) and 56 (93.33%) in group B (cervical cerclage) with p-value of 0.0001.

Conclusion: Conclusion was that prophylactic cervical cerclage is more efficacious than prophylactic vaginal progesterone in women with previous history of preterm birth.

Key Words: preterm birth, progesterone, cervical cerclage

Citation of article: Fayyaz S, Sadaf J, Hafeez S, Aara S, Ajmal A, Malik AM. Comparison of Efficacy of Cervical Cerclage and Vaginal Progesterone in the Prevention of Preterm Labour. Med Forum 2022;33(1):44-47.