13. Association Between Periconceptional Folic Acid Deficiency and Occurrence of Skeletal Anomalies in Newborns
Riasat Ali Nehra1, Noor ul Mobeen1, Akmal Bhatti2 and Hafsa3
ABSTRACT
Objective: This study was planned to detect the connection among environs component (folic acid inadequacy) and development of Skeletal anomalies during intrauterine life.
Study Design: Case control study.
Place and Duration of Study: This study was conducted at the CLAP Hospital Johar Town and Arif Hospital Kasur from 1st January 2014 to 31st Dec. 2014.
Materials and Methods: It was a suitable sampling, two existing groups differing in outcome were identified and compared among, 100 sufferers of CLP and allied skeletal anomalies in neonates age not more than 6 months, in various Hospitals of Lahore. Mothers were asked whether they took folic acid or not during their early pregnancy. Results: The skeletal anomalies number was quite high between mothers having deficiency of folic acid and other vitamins (11% as compared to 2.4% of controls).
Conclusion: Pregnant mothers who have not taken folic acid and other vitamins throughout their early pregnancy developed cleft lip with associated skeletal anomalies in their offspring.
Key Words: Skeletal anomalies, Environmental factors (folic acid and vitamins deficiency).
Citation of articles: Nehra RA, Noor ul Mobeen, Bhatti A, Hafsa. Association Between Periconceptional Folic Acid Deficiency and Occurrence of Skeletal Anomalies in Newborns. Med Forum 2018;29(1):56-59.