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  3. 2. Comparison of Onset of Sensory Block with the Combination of Magnesium Sulphate and Lignocaine versus Lignocaine Alone in Hand and Forearm Surgeries under Intravenous Regional Anesthesia
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2. Comparison of Onset of Sensory Block with the Combination of Magnesium Sulphate and Lignocaine versus Lignocaine Alone in Hand and Forearm Surgeries under Intravenous Regional Anesthesia

Raza Farrukh1, Salman Ather2 and Hashim Imran3

 

ABSTRACT

 

Objective: To compare the mean time of onset of sensory block with the combination of magnesium sulphate and lignocaine versus lignocaine alone in hand and forearm surgeries under intravenous regional anesthesia. Study Design: Randomized Controlled Trial study.

 

Place and Duration of Study: This study was conducted at the Department of Anaesthesiology, DHQ Teaching Hospital Sargodha and Department of Anaesthesiology, Jinnah Hospital Lahore from January 2016 to June 2016. Materials and Methods: Following informed consent, 60 subjects fulfilling the inclusion criteria were selected for the study through non-probability purposive sampling. Subject was randomly assigned to two different anesthetic regimes by using random tables. The experimental group (M) was given lignocaine plus magnesium sulphate as an adjunct and control group (L) was given lignocaine alone for IVRA. The injection was given in 90 seconds by an anesthesiologist blinded to the drug and was to follow up the patient. The sensory block was evaluated every 30 seconds after injection of the drug using a standardized pin-prick technique with a 22-gauge short beveled needle, on a stop watch. The time of onset of complete sensory block in all the dermatomes were noted. The data was collected and analyzed in SPSS version 13.0. T-test was used to compare the mean time for the onset of sensory block in both groups. P-value ≤ 0.05 was significant.

 

Results: The mean age of the patients was noted as 37.97±9.52 years. The mean onset time of sensory block of the patients was noted as 6.58±2.61 minutes. The mean onset time of sensory block in MgSo4 group was noted as 4.13±0.79 minutes whereas the mean onset time of sensory block in Lignocaine group was noted as 9.03±0.94 minutes. Statistically there is highly significant difference between the study groups i.e. p-value=0.000*.

 

Conclusion: It was concluded from results of this study that addition of MgSO4 to lidocaine for intravenous regional anesthesia is beneficial. So in future we will recommend its use along with lidocaine for intravenous regional anesthesia.

 

Key Words: Magnesium Sulphate, Lignocaine, Regional Anesthesia,Sensory block nerve

 

Citation of article: Farrukh R, Ather S, Imran H. Comparison of Onset of Sensory Block with the Combination of Magnesium Sulphate and Lignocaine versus Lignocaine Alone in Hand and Forearm Surgeries under Intravenous Regional Anesthesia. Med Forum 2017;28(6):6-9