2. Efficacy of Lactobacillus Reuteri in Acute Watery Diarrhea
Muhammad Aqeel Khan1, Muhammad Bilal Khattak2, Arshia Munir3 and Irum Naz3
ABSTRACT
Objective: To evaluate the efficacy of lactobacillus reuteri in acute watery diarrhea
Study Design: Randomized Clinical Trial study.
Place and Duration of Study: This study was conducted at the Department Pediatrics, KGMC / HMC Peshawar from 24th April to 23th October 2015
Materials and Methods: This RCT included 96 patients from age 6 to 55 months admitted as a case of acute watery diarrhea were enrolled in the study. After consent taken from attendants, the patients were randomly assigned to one of the study groups; either L. reuteri (5drops or 100 million cfu per day of L. reuterior) or the other group with placebo and the therapy was given for 5 days in each case. The outcome was measured in severity (frequency) and duration of the diseased.
Results: Out of 96 patients, half were subjected to L. reuteri. L.reuteri was given in a dose of 5 drops daily and patients were observed for effectiveness. The effectiveness was observed in 58 patients 24 (50%) from the placebo group and 34 (70%) from the L.reuteri group. This showed that L. reuteri was more effective than placebo in children with acute watery diarrhea with a P value of <0.05.
Conclusion: The study showed that lactobacillus reuteri group not only decreased the severity of the acute watery diarrhea but it also decreased the duration of the disease as compared to the placebo group. Key Words: Acute watery diarrhoea, probiotics, frequency of stools
Citation of article: Khan MA, Khattak MB, Munir A, Naz I. Efficacy of Lactobacillus Reuteri in Acute Watery Diarrhea. Med Forum 2017;28(11):7-11.