23. Evaluation of Morphological Prognostic Factors and Survival Rate in Colorectal Cancer Patients
Kamran1, Mohibullah Khan2 and Ilyas2
ABSTRACT
Objective: To evaluate Morphological Prognostic Factors and Survival Rate in Colorectal Cancer Patients of the recent five years.
Study Design: Retrospective cohort study
Place and Duration of Study: This study was conducted at the in Peshawar Institute of Medical Sciences from June 2014 till August 2019.
Materials and Methods: We collect demographic data in the form of age, sex, body mass index, last date of contact, history of consuming betel nut along with the history of smoking to check the association of cancer with these factors. We include primary site, histological type, grade/differentiation, size of treatment, regional lymph nodes as a general characteristic of tumor. Results: Factors like age greater than 65, high grade of pathological differentiation, distant metastasis were highly associated with a 5-year risk of death among the colorectal cancer patients. Conclusion: Perineural nerve invasion and distant metastasis are considered as important in early detection. Early detection of these parameters will surely increase the survival rate.
Conclusion: There are a lot of prognosis factors that may affect the survival rate among CCR patients. Some independent variables perineural nerve invasion, distant metastasis, age, pathological differentiation grade, obstruction, and regional lymph node metastasis are independent predictors that highly influence the ratio. But some like perineural nerve invasion and distant metastasis are considered as important in early detection. Early detection of these parameters will surely increase the survival rate.
Key Words: Colorectal Cancer, Betal Nut, Smoking, Histopathology
Citation of article: Kamran, Khan M, Ilyas. Evaluation of Morphological Prognostic Factors and Survival Rate in Colorectal Cancer Patients. Med Forum 2020;31(12):102-106.