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27. Validation of Screening Tools and Comparison of Anthropometric Characteristics in Diagnosis of Obstructive Sleep Apnea

Saima Akhter, Nausheen Saifullah, Fatima Zaina, Noureen Durrani and
Mirza Saifullah Baig

ABSTRACT

Objective: To determine the validity and also compare screening questionnaires and anthropometric characteristics in diagnosis of obstructive sleep apnea in Pakistani population.

Study Design: Cross-sectional study

Place and Duration of Study: This study was conducted at the Department of Pulmonology, Jinnah Postgraduate Medical Center Karachi from January 2019 to December 2019.

Materials and Methods: Sixty-nine patients came for sleep study and underwent Polysomnography. Apnea Hypopnea Index ≥5 was considered as positive for OSA.

Results: Forty-one (59.42%) were males and 28 (40.58%) were females with average age of 49.71±10.67 years. All patients underwent PSG and 60 (86.96%) were diagnosed positive for OSA. Patients’ anthropometric characteristics and all four questionnaires were not significantly different among OSA positive and negative except neck circumference (p=0.009). ROC curve showed that the highest AUC was observed for NC which was 0.741 (95% CI: 0.541–0.940, p=0.018) and the optimal cut-off value was ≥40cm. The lowest AUC was 0.522 (95% CI: 0.408–0.635, p=0.701) for Berlin questionnaire. AUC determined for all screening tools excluding NC depicted poor predictive ability of these tests and these tests were not good in discriminating the OSA positive and OSA negative patients.

Conclusion: Neck circumference was independent screening tool to predict OSA. Interestingly screening questionnaires BQ, ESS, SBQ and Mod-ESS are not accurate tool for prediction of OSA in our population.

Key Words: Berlin questionnaire, Epworth Sleepiness Scale, Modified Epworth Sleepiness Scale, Neck Circumference, Obstructive sleep apnea.

Citation of article: Akhter S, Saifullah N, Zaina F, Durrani N, Baig MS. Validation of Screening Tools and Comparison of Anthropometric Characteristics in Diagnosis of Obstructive Sleep Apnea. Med Forum 2021;32(6):107-111.