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5. Obstructive Sleep Apnea and Blood Pressure: A Cross Sectional Study in Our Local Population

Ambreen Qamar1, Hafiz Syed Imran-ul-Haq2, Rashid Ahmed3 and Afsheen Qamar4

ABSTRACT

Objective: To evaluate the association of obstructive sleep apnea with blood pressure in our local population.

Study Design: Cross sectional study

Place and Duration of Study: This study was conducted at the Sleep Laboratory, Polysomnography Dept., Dow University Hospital, Karachi from December 2013 to June 2015.

Materials and Methods: Total 100 subjects were evaluated for study, in which 50 were OSA cases while 50 were control subjects. All subjects were went through informed consent, detailed history, physical examination and ESS score calculation. OSA subjects were examined by overnight polysomnography to confirm diagnosis of OSA and to divide them into groups according to severity of OSA. Systolic and Diastolic blood pressure were evaluated and analyzed by using SPSS version 20.

Results: Mean systolic blood pressure (mm Hg) was significantly higher in cases as compared to the controls (138.60 +  14.07vs 129.40 +14.93) (p <  0.002). Frequency of personswith high blood pressure  was 74% in cases and 30% in controls. Frequency of persons with highblood pressure  was also associated with severity of apnea as it was 30% in control subjects while it was 58.3%, 76.5% and 81.0% in mild apnea, moderate apnea and severe apnea groups respectively.

Conclusion: Study findings are suggesting that obstructive sleep apnea is associated with higher blood pressure; it is also associated with severity of OSA in our population.Our study is emphasizing the need of improving our understanding regarding thepathophysiology of OSA and its relation with hypertension.

Key Words: Obstructive sleep apnea , sleep , Blood pressure

Citation of articles: Qamar A, Haq HIS, Ahmed R, Qamar A. Obstructive Sleep Apnea and Blood Pressure: A Cross Sectional Study in Our Local Population. Med Forum 2018;29(9):18-21.