1. Mushtaq Ahmed 2. Abdul Wali 3. Amjad Ali 

1. Assoc. Prof. of Cardiology, 2. Senior Registrar of Cardiology, 3. Assoc. Prof. Medical B Unit, Mardan Medical Complex Teaching Hospital, Bacha Khan Medical College, Mardan 

ABSTRACT

Objective: The aim of our study was to determine outcomes of fibrinolytics in patients of acute MI in a setup where streptokinase is the sole fibrinolytic used and where the facility of primary PCI is not available.

Study Design: Descriptive cross sectional study

Place and Duration of Study: This study was conducted at the Department of Cardiology, Mardan Medical Complex Teaching Hospital, Mardan from January 2011 to December 2014.   

Materials and Methods: This study included 3,000 patients using non probability purposive sampling technique. The study was approved by the Hospital Ethical Committee. An informed written consent was obtained. Out of these, 2100 (70%) were non diabetic and 900 (30%) diabetics.

Results: Those who presented within 6 hours of the index chest pain, streptokinase therapy was successful in 1709 (57%) patients and unsuccessful in 197 (6.6%) patients. Streptokinase was successful only in 771 (25.7%) patients and unsuccessful in 323 (10.8%) patients who presented in 6-12 hours of the index pain.  Reinfarction occurred in 193 (6.4%) patients whereas 2807 (93.6%) were free of reinfarction. Hemorrhagic Stroke occurred 50 (1.7%) patients whereas 2 (0.1%) developed ischemic stroke.  

Conclusion: Our study convincingly showed that intra cranial hemorrhage was relatively low with this fibrinolytic. Key Words: Fibrinolytics, Acute Myocardial Infarction, Patients

Citation of article: Ahmed M, Wali A, Ali A. Outcomes of Fibrinolytics in Patients of Acute Myocardial