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  3. 7. To Assess the Accuracy of Fine Needle Aspiration Cytology (FNAC) for Diagnosis of Malignancy in Solitary Thyroid Nodule at Civil Hospital Karachi
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7. To Assess the Accuracy of Fine Needle Aspiration Cytology (FNAC) for Diagnosis of Malignancy in Solitary Thyroid Nodule at Civil Hospital Karachi

1. Abrar Hussain Shah 2. Atif Hafeez 3. Adnan Ejaz 4. Saleem Marfani

1. Asstt. Prof. of ENT, Azra Naheed Medical College Lahore 2. Asstt. Prof. of ENT, CHK DUHS, Karachi 3. Assoc.

Prof. of ENT, Azra Naheed Medical College Lahore 4. Prof. of ENT, DUHS &CHK Karachi

ABSTRACT

Objective: To assess the accuracy of fine needle aspiration cytology (FNAC) for the diagnosis of malignancy in solitary thyroid nodule.

Study Design:  Observational / Descriptive study  

Place and Duration of Study: This study was conducted in the department of otolaryngology and Head and Neck Surgery at Civil Hospital Karachi from January 2007 to July 2008.   

Materials and Methods: This study comprises of 70 cases in one and half years. We have included all cases of solitary nodule of either sex more than 10 years and excluded those patients who were exposed to radiation or underwent any sort of neck surgery previously. All Patients with solitary thyroid nodule were investigated with routine hematological and biochemical tests, thyroid profile, thyroid Scan, ultra sound neck and FNAC in outpatient department. At admission all risks/benefits of surgical procedures were explained to patients. Postoperative histopathological report of specimen was compared with preoperative fine needle aspiration cytology.

Results: In our 70 cases study 59 patients were diagnosed with benign and 11 with malignant disease. Sensitivity, specificity, accuracy was also recorded which were 72.72%, 99.20% and 94.20% respectively. Papillary carcinoma was found most common tumor in 63.63%.

Conclusion: FNAC is valuable investigation for the preoperative assessment of solitary thyroid nodule and also has high diagnostic accuracy in its evaluation.

Key Words: Solitary thyroid nodule, FNAC, Papillary carcinoma

Citation of article: Shah AH, Hafeez A, Ejaz A, Marfani S. To Assess the Accuracy of Fine Needle Aspiration

Cytology (FNAC) for Diagnosis of Malignancy in Solitary Thyroid Nodule at Civil Hospital Karachi. Med


Forum 2015;26(12):26-28.