Search Submit Your Manuscript

Become A Member

  1. Home
  2. Novemeber 2015
  3. 5. Celiac Disease; A Hidden Cause of Iron Deficiency Anemia?
Article Image

5. Celiac Disease; A Hidden Cause of Iron Deficiency Anemia?

1. Rakhshinda Jabeen 2. Hussain Haroon 3. Fawad Qureshi 4. Syed Shirjeel Husain 

5. Asma Zishan

1. Assoc. Prof., Med Unit I, Civil Hospital Karachi 2. Asstt. Prof., Med Unit II, Civil Hospital Karachi 3. Consultant

Physician, Shaukat Khanam Memorial Hospital, Karachi 4. Resident Medicine, Med Unit IV, Civil Hospital Karachi

5. Specialist, Rustaq Hospital, MOH, Oman


Objective: The aim of the study is to determine frequency of celiac disease in adults with inexplicable iron deficiency Anemia

Study Design: Cross-sectional / observational study 

Place and Duration of Study: This study was conducted at all Medical units of Civil Hospital Karachi from December 2009 to June 2010.

Materials and Methods: The study included diagnosed cases of Iron Deficiency Anemia on basis of Iron profile without evident reason.  They were evaluated for celiac disease on the basis of serological markers i.e. tissue transglutaminase antibodies (TTG) IgA type via standard laboratory procedures.

Results: A total of 100 patients with Iron deficiency anemia previously diagnosed on basis of serum levels were included in this study. The average age was 37.12+ 8.2years and 44 (44%) were males.

Celiac disease was found via serology in 16 (16%) of the patients. Out of these 16 Celiac disease patients 7 (43.75%) were males and 9 (56.25%) were females with 1:1.28 male to female ratio. 

Conclusion: Celiac disease is an important cause of inexplicable Iron deficiency anemia especially in absence of gastro-intestinal symptoms. Serology though less sensitive, but can be an important screening tool for these patients.  Key Words: Iron Deficiency Anemia, Celiac disease, Tissue Transglutaminase antibody IgA.

Citation of article: Jabeen R, Haroon H, Qureshi F, Husain SS, Zishan A. Celiac Disease; A Hidden Cause of Iron Deficiency Anemia? Med Forum 2015;26(11):18-21.